By M.V. Nermut and A.C. Steven (Eds.)
Animal Virus constitution presents a entire, state of the art precis of the constitution, molecular composition, and imperative antigenic and organic homes of every at present famous kin of animal viruses. info deriving from electron microscopy, computing device photo processing and X-ray diffraction is built-in systematically with biochemical information into third-dimensional molecular versions of viral structure. a quick account of virus/cell interplay and pathogenicity completes every one bankruptcy.
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Extra resources for Animal Virus Structure
In paramyxoviruses and poxviruses). Similar effects can be achieved by prefixation with glutaraldehyde or osmium tetroxide. 2. Shadowing techniques One of the first methods used to increase contrast of viruses in the electron microscope was unidirectional shadow-casting with chromium. Neglected for a decade, it has been resurrected with the advent of freeze-fracturing and freezedrying and has become a valuable tool for the visualization of virus nucleic acids and viral components, in particular after freeze-fracturing.
1985) Low-temperature methods in biological electron microscopy. In Practical Methods in Electron Microscopy, Ed. M. Glauert, Vol. 10. Elsevier Biomedical, Amsterdam. A. W. (1984) The pleated sheet: an unusual negative-staining method for transmission electron microscopy of biological macromolecules. J. Ultrastruct. Res. 89, 111-122. M. R. (1968) Regulation of glutamine synthetase. XII. Electron microscopy of the enzyme from Escherichza coli. Biochemistry 7, 2143-2152. C. (1953a) A method of freeze-drying for electron microscopy.
Horne and Dr. R. Ruigrok for helpful comments on the manuscript and in particular Dr. C. Steven for heIpfu1 criticisms and long-lasting discussions of the fundamental problems in this chapter. M. (1984) Structural investigation of hexon, the major coat protein of adenovirus. In Biological Macromolecules and Assemblies, Eds. A. Jurnak and A. McPherson; Vol. 1: Virus Structures, pp. 337-385. J . Wiley & Sons, New York. D. and Klug, A. (1962) Physical principles in the construction of regular viruses.
Animal Virus Structure by M.V. Nermut and A.C. Steven (Eds.)